Kazuhiro Tsuruma Selected Research

SUN N8075

1/2011	SUN N8075, a novel radical scavenger, protects against retinal cell death in mice.
12/2010	An inducer of VGF protects cells against ER stress-induced cell death and prolongs survival in the mutant SOD1 animal models of familial ALS.

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Kazuhiro Tsuruma Research Topics

Disease

13	Ischemia 11/2016 - 05/2004
12	Ganglion Cysts (Ganglion) 10/2017 - 01/2011
11	Brain Ischemia (Cerebral Ischemia) 07/2018 - 03/2009
10	Retinal Degeneration 01/2018 - 12/2010
9	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 10/2016 - 10/2009
8	Macular Degeneration (Age-Related Maculopathy) 01/2018 - 02/2011
7	Retinal Diseases 01/2018 - 01/2011
6	Choroidal Neovascularization 01/2018 - 09/2014
6	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2017 - 10/2011
6	Melanoma (Melanoma, Malignant) 01/2017 - 01/2012
6	Infarction (Infarctions) 01/2017 - 03/2009
6	Neoplasms (Cancer) 12/2016 - 11/2009
6	Hypoxia (Hypoxemia) 04/2015 - 06/2008
5	Inflammation (Inflammations) 07/2018 - 08/2013
5	Stroke (Strokes) 04/2015 - 07/2011
5	Retinal Neovascularization 01/2013 - 01/2010
4	Blindness (Hysterical Blindness) 01/2018 - 02/2011
4	Glaucoma 03/2017 - 11/2011
4	Reperfusion Injury 10/2016 - 10/2009
4	Ischemic Stroke 10/2016 - 06/2012
3	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 07/2018 - 02/2016
3	Alzheimer Disease (Alzheimer's Disease) 05/2017 - 10/2009
3	Neurodegenerative Diseases (Neurodegenerative Disease) 05/2017 - 10/2009
3	Atrophy 06/2013 - 12/2010
3	Constipation 10/2012 - 01/2010
3	Neuroblastoma 06/2012 - 06/2008
3	Cerebral Infarction 07/2011 - 10/2009
3	Diabetic Retinopathy (Retinopathy, Diabetic) 05/2011 - 11/2009
2	Cerebral Hemorrhage 01/2017 - 01/2017
2	Brain Injuries (Brain Injury) 01/2017 - 03/2009
2	Memory Disorders (Memory Loss) 01/2015 - 10/2009
2	Brain Edema (Cerebral Edema) 10/2013 - 12/2010
2	Disease Progression 07/2013 - 12/2010
2	Stomach Ulcer (Gastric Ulcer) 10/2012 - 08/2012
2	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2012 - 02/2011
2	Hyperoxia 05/2011 - 01/2010
2	Transient Ischemic Attack 11/2010 - 10/2009
1	Sepsis (Septicemia) 07/2018
1	Motor Neuron Disease (Primary Lateral Sclerosis) 07/2018
1	Fibrosis (Cirrhosis) 07/2018
1	Schizophrenia (Dementia Praecox) 06/2018
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2018
1	Hematoma 01/2017
1	Retinal Vein Occlusion 01/2017

Drug/Important Bio-Agent (IBA)

20	Retinaldehyde (Retinal)IBA 01/2018 - 01/2011
10	Neuroprotective AgentsIBA 01/2017 - 10/2009
7	Oxygen (Dioxygen)IBA 01/2018 - 02/2011
7	Proteins (Proteins, Gene)FDA Link 01/2017 - 11/2010
6	Glycoproteins (Glycoprotein)IBA 01/2017 - 01/2012
6	IgA receptor (protein B)IBA 01/2017 - 01/2012
6	Cilostazol (Pletal)FDA LinkGeneric 01/2017 - 03/2009
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 11/2009
4	EdaravoneIBA 11/2017 - 09/2010
4	ProgranulinsIBA 10/2017 - 08/2013
4	AntioxidantsIBA 11/2016 - 08/2012
4	Type 3 Cyclic Nucleotide PhosphodiesterasesIBA 10/2013 - 12/2010
4	TunicamycinIBA 01/2013 - 01/2011
3	astaxanthine (astaxanthin)IBA 11/2016 - 01/2011
3	Free Radical ScavengersIBA 01/2016 - 09/2010
3	Sigma-1 ReceptorIBA 03/2015 - 05/2013
3	LaxativesIBA 10/2012 - 01/2010
2	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 03/2017 - 01/2012
2	AnticoagulantsIBA 01/2017 - 10/2013
2	Pharmaceutical PreparationsIBA 01/2017 - 07/2016
2	Warfarin (Coumadin)FDA LinkGeneric 01/2017 - 10/2013
2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2017 - 03/2009
2	Adenosine Triphosphatases (ATPase)IBA 12/2016 - 03/2016
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2016 - 08/2013
2	Glucose (Dextrose)FDA LinkGeneric 09/2014 - 05/2010
2	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2013 - 08/2013
2	Conditioned Culture MediaIBA 11/2013 - 06/2012
2	N-Methylaspartate (NMDA)IBA 08/2013 - 09/2011
2	trans-sodium crocetinate (crocetin)IBA 03/2013 - 01/2011
2	Claudin-5IBA 02/2013 - 12/2010
2	Metallothionein 3IBA 11/2012 - 10/2009
2	Loperamide (Imodium)FDA LinkGeneric 10/2012 - 01/2010
2	Biological ProductsIBA 10/2012 - 01/2011
2	Ethanol (Ethyl Alcohol)IBA 08/2012 - 11/2010
2	SUN N8075IBA 01/2011 - 12/2010
2	CaspasesIBA 01/2011 - 06/2008
1	7,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA 07/2018
1	Docosahexaenoic AcidsIBA 07/2018
1	Antipsychotic Agents (Antipsychotics)IBA 06/2018
1	Prednisolone (Predate)FDA LinkGeneric 01/2018
1	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 01/2018
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2018
1	CannabinoidsIBA 01/2018
1	EndocannabinoidsIBA 05/2017
1	RimonabantIBA 05/2017
1	AntibodiesIBA 01/2017
1	RivaroxabanIBA 01/2017
1	Liposomes (Liposome)IBA 01/2017
1	arginyl- 2,'6'- dimethyltyrosyl- lysyl- phenylalaninamideIBA 01/2017
1	Thrombin FDA Link 01/2017
1	Oxidoreductases (Dehydrogenase)IBA 01/2017
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2017

Therapy/Procedure

11	Therapeutics 01/2018 - 12/2010
8	Lasers (Laser) 01/2018 - 03/2011
4	Ligation 11/2016 - 12/2011
2	Light Coagulation 01/2012 - 03/2011